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Chitosan grafted methoxy poly(ethylene glycol)-poly(ε-caprolactone) nanosuspension for ocular delivery of hydrophobic diclofenac
This study aimed to develop a cationic nanosuspension of chitosan (CS) and methoxy poly(ethylene glycol)-poly(ε-caprolactone) (MPEG-PCL) for ocular delivery of diclofenac (DIC). MPEG-PCL-CS block polymer was synthesized by covalent coupling of MPEG-PCL with CS. The critical micelle concentration of...
Autores principales: | Shi, Shuai, Zhang, Zhaoliang, Luo, Zichao, Yu, Jing, Liang, Renlong, Li, Xingyi, Chen, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464308/ https://www.ncbi.nlm.nih.gov/pubmed/26067670 http://dx.doi.org/10.1038/srep11337 |
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