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An overview of platelet indices for evaluating platelet function in children with scorpion envenomation

The aim of this study was to assess the correlation between platelet indices and scorpion envenomations (SE). Medical records of 76 children who were hospitalised for scorpion stings in the paediatric intensive care unit (PICU) between February 2013 and November 2013, and 55 healthy children who wer...

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Autores principales: Konca, Capan, Tekin, Mehmet, Colak, Pinar, Uckardes, Fatih, Turgut, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464311/
https://www.ncbi.nlm.nih.gov/pubmed/26417303
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author Konca, Capan
Tekin, Mehmet
Colak, Pinar
Uckardes, Fatih
Turgut, Mehmet
author_facet Konca, Capan
Tekin, Mehmet
Colak, Pinar
Uckardes, Fatih
Turgut, Mehmet
author_sort Konca, Capan
collection PubMed
description The aim of this study was to assess the correlation between platelet indices and scorpion envenomations (SE). Medical records of 76 children who were hospitalised for scorpion stings in the paediatric intensive care unit (PICU) between February 2013 and November 2013, and 55 healthy children who were similar to the patient group in terms of age and sex, were analysed retrospectively. The leucocyte (WBC), thrombocyte (PLT), plateletcrit (PCT), platelet distribution width (PDW) and mean platelet volume (MPV) values of the 76 children with SE were recorded. These values were compared with the healthy control group. Significantly higher WBC and PDW values were noted in patients with SE in comparison to the controls. Patients with SE had significantly lower mean MPV values compared to the healthy controls (9.03 ± 1.26 compared to 10.43 ± 1.44 fL, respectively; p < 0.001). Although the mean platelet count was slightly elevated in the SE group, no statistically significant difference existed between the two groups (p = 0.097). Furthermore, the mean PCT values in the SE group compared to the control group were slightly decreased, but this decrease was not statistically significant (p = 0.141). A significant inverse correlation existed between the MPV values and the WBC (r = -0.450, p < 0.01) and PLT counts (r = -0.420, p < 0.01). The PLT values were significantly correlated with the PCT values (r = 0.687, p < 0.01). This study demonstrated that SE may lead to several alterations in platelet indices. Significantly lower values of MPV and higher values of PDW were detected in SE patients. However, the increase in the platelet counts and the decrease in the PCT values were not significant.
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spelling pubmed-44643112015-09-28 An overview of platelet indices for evaluating platelet function in children with scorpion envenomation Konca, Capan Tekin, Mehmet Colak, Pinar Uckardes, Fatih Turgut, Mehmet EXCLI J Original Article The aim of this study was to assess the correlation between platelet indices and scorpion envenomations (SE). Medical records of 76 children who were hospitalised for scorpion stings in the paediatric intensive care unit (PICU) between February 2013 and November 2013, and 55 healthy children who were similar to the patient group in terms of age and sex, were analysed retrospectively. The leucocyte (WBC), thrombocyte (PLT), plateletcrit (PCT), platelet distribution width (PDW) and mean platelet volume (MPV) values of the 76 children with SE were recorded. These values were compared with the healthy control group. Significantly higher WBC and PDW values were noted in patients with SE in comparison to the controls. Patients with SE had significantly lower mean MPV values compared to the healthy controls (9.03 ± 1.26 compared to 10.43 ± 1.44 fL, respectively; p < 0.001). Although the mean platelet count was slightly elevated in the SE group, no statistically significant difference existed between the two groups (p = 0.097). Furthermore, the mean PCT values in the SE group compared to the control group were slightly decreased, but this decrease was not statistically significant (p = 0.141). A significant inverse correlation existed between the MPV values and the WBC (r = -0.450, p < 0.01) and PLT counts (r = -0.420, p < 0.01). The PLT values were significantly correlated with the PCT values (r = 0.687, p < 0.01). This study demonstrated that SE may lead to several alterations in platelet indices. Significantly lower values of MPV and higher values of PDW were detected in SE patients. However, the increase in the platelet counts and the decrease in the PCT values were not significant. Leibniz Research Centre for Working Environment and Human Factors 2014-07-25 /pmc/articles/PMC4464311/ /pubmed/26417303 Text en Copyright © 2014 Konca et al. http://www.excli.de/documents/assignment_of_rights.pdf This is an Open Access article distributed under the following Assignment of Rights http://www.excli.de/documents/assignment_of_rights.pdf. You are free to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Original Article
Konca, Capan
Tekin, Mehmet
Colak, Pinar
Uckardes, Fatih
Turgut, Mehmet
An overview of platelet indices for evaluating platelet function in children with scorpion envenomation
title An overview of platelet indices for evaluating platelet function in children with scorpion envenomation
title_full An overview of platelet indices for evaluating platelet function in children with scorpion envenomation
title_fullStr An overview of platelet indices for evaluating platelet function in children with scorpion envenomation
title_full_unstemmed An overview of platelet indices for evaluating platelet function in children with scorpion envenomation
title_short An overview of platelet indices for evaluating platelet function in children with scorpion envenomation
title_sort overview of platelet indices for evaluating platelet function in children with scorpion envenomation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464311/
https://www.ncbi.nlm.nih.gov/pubmed/26417303
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