Cargando…
Novel stereocontrolled syntheses of tashiromine and epitashiromine
A novel stereocontrolled approach has been developed for the syntheses of tashiromine and epitashiromine alkaloids from cyclooctene β-amino acids. The synthetic concept is based on the azetidinone opening of a bicyclic β-lactam, followed by oxidative ring opening through ring C–C double bond and red...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464356/ https://www.ncbi.nlm.nih.gov/pubmed/26124861 http://dx.doi.org/10.3762/bjoc.11.66 |
| _version_ | 1782375950657257472 |
|---|---|
| author | Kiss, Loránd Forró, Enikő Fülöp, Ferenc |
| author_facet | Kiss, Loránd Forró, Enikő Fülöp, Ferenc |
| author_sort | Kiss, Loránd |
| collection | PubMed |
| description | A novel stereocontrolled approach has been developed for the syntheses of tashiromine and epitashiromine alkaloids from cyclooctene β-amino acids. The synthetic concept is based on the azetidinone opening of a bicyclic β-lactam, followed by oxidative ring opening through ring C–C double bond and reductive ring-closure reactions of the cis- or trans-cyclooctene β-amino acids. |
| format | Online Article Text |
| id | pubmed-4464356 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-44643562015-06-29 Novel stereocontrolled syntheses of tashiromine and epitashiromine Kiss, Loránd Forró, Enikő Fülöp, Ferenc Beilstein J Org Chem Full Research Paper A novel stereocontrolled approach has been developed for the syntheses of tashiromine and epitashiromine alkaloids from cyclooctene β-amino acids. The synthetic concept is based on the azetidinone opening of a bicyclic β-lactam, followed by oxidative ring opening through ring C–C double bond and reductive ring-closure reactions of the cis- or trans-cyclooctene β-amino acids. Beilstein-Institut 2015-04-30 /pmc/articles/PMC4464356/ /pubmed/26124861 http://dx.doi.org/10.3762/bjoc.11.66 Text en Copyright © 2015, Kiss et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Kiss, Loránd Forró, Enikő Fülöp, Ferenc Novel stereocontrolled syntheses of tashiromine and epitashiromine |
| title | Novel stereocontrolled syntheses of tashiromine and epitashiromine |
| title_full | Novel stereocontrolled syntheses of tashiromine and epitashiromine |
| title_fullStr | Novel stereocontrolled syntheses of tashiromine and epitashiromine |
| title_full_unstemmed | Novel stereocontrolled syntheses of tashiromine and epitashiromine |
| title_short | Novel stereocontrolled syntheses of tashiromine and epitashiromine |
| title_sort | novel stereocontrolled syntheses of tashiromine and epitashiromine |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464356/ https://www.ncbi.nlm.nih.gov/pubmed/26124861 http://dx.doi.org/10.3762/bjoc.11.66 |
| work_keys_str_mv | AT kisslorand novelstereocontrolledsynthesesoftashiromineandepitashiromine AT forroeniko novelstereocontrolledsynthesesoftashiromineandepitashiromine AT fulopferenc novelstereocontrolledsynthesesoftashiromineandepitashiromine |