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Effects of acute and sustained administration of vortioxetine on the serotonin system in the hippocampus: electrophysiological studies in the rat brain
RATIONALE: Vortioxetine is a novel multimodal antidepressant that is a 5-HT(1B) receptor partial agonist, a 5-HT(1A) receptor agonist, an inhibitor of the serotonin (5-HT) transporter, and a 5-HT(1D), 5-HT(3), and 5-HT(7) receptor antagonist in vitro. In vivo studies have shown that vortioxetine enh...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464372/ https://www.ncbi.nlm.nih.gov/pubmed/25665528 http://dx.doi.org/10.1007/s00213-015-3870-9 |