Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury

Overactivation of poly (ADP-ribose) polymerase 1 (PARP-1), as a result of sustained DNA oxidation in ischemia-reperfusion injury, triggers programmed cell necrosis and apoptosis. The present study was conducted to demonstrate whether hydrogen-rich saline (HRS) has a neuroprotective effect on retinal...

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Detalles Bibliográficos
Autores principales: LIU, HONGWEI, HUA, NING, XIE, KELIANG, ZHAO, TINGTING, YU, YONGHAO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464386/
https://www.ncbi.nlm.nih.gov/pubmed/25954991
http://dx.doi.org/10.3892/mmr.2015.3731

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