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Multivalent dendritic polyglycerolamine with arginine and histidine end groups for efficient siRNA transfection

The success of siRNA-based therapeutics highly depends on a safe and efficient delivery of siRNA into the cytosol. In this study, we post-modified the primary amines on dendritic polyglycerolamine (dPG-NH(2)) with different ratios of two relevant amino acids, namely, arginine (Arg) and histidine (Hi...

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Detalles Bibliográficos
Autores principales:	Sheikhi Mehrabadi, Fatemeh, Zeng, Hanxiang, Johnson, Mark, Schlesener, Cathleen, Guan, Zhibin, Haag, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2015
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464416/ https://www.ncbi.nlm.nih.gov/pubmed/26124878 http://dx.doi.org/10.3762/bjoc.11.86

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