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Inhibition of autophagy using 3-methyladenine increases cisplatin-induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells

Cisplatin is one of the most widely used chemotherapeutic drugs; however, the side effects and drug resistance limit its usage. Previous findings have demonstrated that cisplatin kills tumor cells through endoplasmic reticulum (ER) stress, which provides a novel method to minimize cisplatin toxicity...

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Detalles Bibliográficos
Autores principales:	ZHANG, RUIJIAN, WANG, RUIJUN, CHEN, QIANXUE, CHANG, HONG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464427/ https://www.ncbi.nlm.nih.gov/pubmed/25846607 http://dx.doi.org/10.3892/mmr.2015.3588

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