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Low expression of phosphatase and tensin homolog in clear-cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway

Clear-cell renal cell carcinoma (CCRCC) is the most frequent primary malignancy in the adult kidney. Most patients with advanced CCRCC have poor prognosis as CCRCC remains resistant to chemotherapy. The present study explored the possible mechanism underlying CCRCC resistance to chemotherapy and fou...

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Detalles Bibliográficos
Autores principales:	CHEN, JUN, ZHU, HE, ZHANG, YAN, CUI, MAN-HUA, HAN, LI-YING, JIA, ZHAN-HUI, WANG, LING, TENG, HONG, MIAO, LI-NING
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464461/ https://www.ncbi.nlm.nih.gov/pubmed/25954860 http://dx.doi.org/10.3892/mmr.2015.3740

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