Cargando…

Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy

The Warburg effect and tumor hypoxia underlie a unique cancer metabolic phenotype characterized by glucose dependency and aerobic fermentation. We previously showed that two non-toxic metabolic therapies – the ketogenic diet with concurrent hyperbaric oxygen (KD+HBOT) and dietary ketone supplementat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poff, A. M., Ward, N., Seyfried, T. N., Arnold, P., D’Agostino, D. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464523/ https://www.ncbi.nlm.nih.gov/pubmed/26061868 http://dx.doi.org/10.1371/journal.pone.0127407

Ejemplares similares

The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer
por: Poff, Angela M., et al.
Publicado: (2013)

Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer
por: Poff, AM, et al.
Publicado: (2014)

Delaying latency to hyperbaric oxygen‐induced CNS oxygen toxicity seizures by combinations of exogenous ketone supplements
por: Ari, Csilla, et al.
Publicado: (2019)

Ketone Supplementation: Meeting the Needs of the Brain in an Energy Crisis
por: Poff, Angela M., et al.
Publicado: (2021)

Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague–Dawley rats
por: Kesl, Shannon L., et al.
Publicado: (2016)

Complex I inhibition augments dichloroacetate cytotoxicity through enhancing oxidative stress in VM-M3 glioblastoma cells
por: Ward, Nathan P., et al.
Publicado: (2017)

Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives
por: Poff, Angela M., et al.
Publicado: (2019)

Genetic variants for personalised management of very low carbohydrate ketogenic diets
por: Aronica, Lucia, et al.
Publicado: (2020)

Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats
por: Ari, Csilla, et al.
Publicado: (2016)

Commentary: Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists
por: Stubbs, Brianna J., et al.
Publicado: (2018)

Corrigendum: Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats
por: Ari, Csilla, et al.
Publicado: (2017)

Ketone Bodies Attenuate Wasting in Models of Atrophy
por: Koutnik, Andrew P., et al.
Publicado: (2020)

Starvation Ketoacidosis Induced by Ketogenic Diet and Consumption of Ketone Supplement
por: Malhi, Manjot S, et al.
Publicado: (2021)

Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer
por: İyikesici, Mehmet Salih, et al.
Publicado: (2017)

Ganglioside composition and histology of a spontaneous metastatic brain tumour in the VM mouse
por: El-Abbadi, M, et al.
Publicado: (2001)

Cancer as a metabolic disease: implications for novel therapeutics
por: Seyfried, Thomas N., et al.
Publicado: (2014)

Acute Ketogenic Diet and Ketone Ester Supplementation Impairs Race Walk Performance
por: WHITFIELD, JAMIE, et al.
Publicado: (2021)

Effects of Hyperbaric Oxygen Preconditioning on Doxorubicin Cardiorespiratory Toxicity
por: Doerr, Vivian, et al.
Publicado: (2022)

Age- and Sex-Dependent Modulation of Exogenous Ketone Supplement-Evoked Effects on Blood Glucose and Ketone Body Levels in Wistar Albino Glaxo Rijswijk Rats
por: Kovács, Zsolt, et al.
Publicado: (2021)

The 1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt Supplementation on Multi-Organ Markers of Oxidative Stress and Mitochondrial Function in Rats
por: Kephart, Wesley C., et al.
Publicado: (2017)

The Ketogenic Diet Revisited: Beyond Ketones
por: Sourbron, Jo, et al.
Publicado: (2021)

Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies
por: Mantis, John G, et al.
Publicado: (2004)

Efficacy and Safety of Ketone Supplementation or Ketogenic Diets for Alzheimer's Disease: A Mini Review
por: Lilamand, Matthieu, et al.
Publicado: (2022)

Exogenous Ketone Supplementation and Ketogenic Diets for Exercise: Considering the Effect on Skeletal Muscle Metabolism
por: Khouri, Hannah, et al.
Publicado: (2023)

Exogenous Ketone Supplements Improved Motor Performance in Preclinical Rodent Models
por: Ari, Csilla, et al.
Publicado: (2020)

Effects of an Exogenous Ketone Supplement on Five‐Kilometer Running Performance
por: Prins, Philip J., et al.
Publicado: (2020)

Impact of ketogenic diet and ketone diester supplementation on body weight, blood glucose, and ketones in Sprague Dawley rats fed over two weeks
por: Modica, LT Claire M., et al.
Publicado: (2021)

Anxiolytic Effect of Exogenous Ketone Supplementation Is Abolished by Adenosine A1 Receptor Inhibition in Wistar Albino Glaxo/Rijswijk Rats
por: Kovács, Zsolt, et al.
Publicado: (2018)

Concentration-Dependent Effects of a Dietary Ketone Ester on Components of Energy Balance in Mice
por: Deemer, Sarah E., et al.
Publicado: (2019)

Therapeutic Potential of Exogenous Ketone Supplement Induced Ketosis in the Treatment of Psychiatric Disorders: Review of Current Literature
por: Kovács, Zsolt, et al.
Publicado: (2019)

Exogenous Ketone Supplementation Decreased the Lipopolysaccharide-Induced Increase in Absence Epileptic Activity in Wistar Albino Glaxo Rijswijk Rats
por: Kovács, Zsolt, et al.
Publicado: (2019)

Adenosine A1 Receptor Antagonism Abolished the Anti-seizure Effects of Exogenous Ketone Supplementation in Wistar Albino Glaxo Rijswijk Rats
por: Kovács, Zsolt, et al.
Publicado: (2017)

Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats
por: Brunner, Brigitta, et al.
Publicado: (2021)

Enhancement of Ketone Supplements-Evoked Effect on Absence Epileptic Activity by Co-Administration of Uridine in Wistar Albino Glaxo Rijswijk Rats
por: Brunner, Brigitta, et al.
Publicado: (2021)

Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse
por: Shelton, Laura M, et al.
Publicado: (2010)

Ketone supplementation abolished isoflurane anesthesia-induced elevation in blood glucose level and increased recovery time from anesthesia in Wistar Albino Glaxo Rijswijk rats
por: Kovács, Zsolt, et al.
Publicado: (2023)

Markers of Pulmonary Oxygen Toxicity in Hyperbaric Oxygen Therapy Using Exhaled Breath Analysis
por: Wingelaar, T. T., et al.
Publicado: (2019)

Nontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma
por: Augur, Zachary M., et al.
Publicado: (2018)

Ketogenic diets and Ketone suplementation: A strategy for therapeutic intervention
por: Saris, Christiaan G. J., et al.
Publicado: (2022)

Ketogenic diet versus ketoacidosis: what determines the influence of ketone bodies on neurons?
por: Fedorovich, Sergei V., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_apnb0ub7o47qllt2k364qm42tb