Cargando…

CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols

Glycerol is an attractive renewable building block for the synthesis of polyglycerols, which find application in the cosmetic and pharmaceutical industries. The selective etherification of glycerol to higher oligomers was studied in the presence of CaO colloids and the data are compared with those o...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirby, Fiona, Nieuwelink, Anne-Eva, Kuipers, Bonny W M, Kaiser, Anton, Bruijnincx, Pieter C A, Weckhuysen, Bert M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464545/
https://www.ncbi.nlm.nih.gov/pubmed/25684403
http://dx.doi.org/10.1002/chem.201405906
_version_ 1782375995643265024
author Kirby, Fiona
Nieuwelink, Anne-Eva
Kuipers, Bonny W M
Kaiser, Anton
Bruijnincx, Pieter C A
Weckhuysen, Bert M
author_facet Kirby, Fiona
Nieuwelink, Anne-Eva
Kuipers, Bonny W M
Kaiser, Anton
Bruijnincx, Pieter C A
Weckhuysen, Bert M
author_sort Kirby, Fiona
collection PubMed
description Glycerol is an attractive renewable building block for the synthesis of polyglycerols, which find application in the cosmetic and pharmaceutical industries. The selective etherification of glycerol to higher oligomers was studied in the presence of CaO colloids and the data are compared with those obtained from NaOH and CaO. The materials were prepared by dispersing CaO, CaCO(3), or Ca(OH)(2) onto a carbon nanofiber (CNF) support. Colloidal nanoparticles were subsequently dispensed from the CNF into the reaction mixture to give CaO colloids that have a higher activity than equimolar amounts of bulk CaO and NaOH. Optimization of the reaction conditions allowed us to obtain a product with Gardner color number <2, containing no acrolein and minimal cyclic byproducts. The differences in the CaO colloids originating from CNF and bulk CaO were probed using light scattering and conductivity measurements. The results confirmed that the higher activity of the colloids originating from CaO/CNF was due to their more rapid formation and smaller size compared with colloids from bulk CaO. We thus have developed a practical method for the synthesis of polyglycerols containing low amounts of Ca.
format Online
Article
Text
id pubmed-4464545
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher WILEY-VCH Verlag
record_format MEDLINE/PubMed
spelling pubmed-44645452015-06-17 CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols Kirby, Fiona Nieuwelink, Anne-Eva Kuipers, Bonny W M Kaiser, Anton Bruijnincx, Pieter C A Weckhuysen, Bert M Chemistry Full Papers Glycerol is an attractive renewable building block for the synthesis of polyglycerols, which find application in the cosmetic and pharmaceutical industries. The selective etherification of glycerol to higher oligomers was studied in the presence of CaO colloids and the data are compared with those obtained from NaOH and CaO. The materials were prepared by dispersing CaO, CaCO(3), or Ca(OH)(2) onto a carbon nanofiber (CNF) support. Colloidal nanoparticles were subsequently dispensed from the CNF into the reaction mixture to give CaO colloids that have a higher activity than equimolar amounts of bulk CaO and NaOH. Optimization of the reaction conditions allowed us to obtain a product with Gardner color number <2, containing no acrolein and minimal cyclic byproducts. The differences in the CaO colloids originating from CNF and bulk CaO were probed using light scattering and conductivity measurements. The results confirmed that the higher activity of the colloids originating from CaO/CNF was due to their more rapid formation and smaller size compared with colloids from bulk CaO. We thus have developed a practical method for the synthesis of polyglycerols containing low amounts of Ca. WILEY-VCH Verlag 2015-03-23 2015-02-13 /pmc/articles/PMC4464545/ /pubmed/25684403 http://dx.doi.org/10.1002/chem.201405906 Text en © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the terms of the Creative Commons Attribution Non-Commercial NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Full Papers
Kirby, Fiona
Nieuwelink, Anne-Eva
Kuipers, Bonny W M
Kaiser, Anton
Bruijnincx, Pieter C A
Weckhuysen, Bert M
CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols
title CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols
title_full CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols
title_fullStr CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols
title_full_unstemmed CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols
title_short CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols
title_sort cao as drop-in colloidal catalysts for the synthesis of higher polyglycerols
topic Full Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464545/
https://www.ncbi.nlm.nih.gov/pubmed/25684403
http://dx.doi.org/10.1002/chem.201405906
work_keys_str_mv AT kirbyfiona caoasdropincolloidalcatalystsforthesynthesisofhigherpolyglycerols
AT nieuwelinkanneeva caoasdropincolloidalcatalystsforthesynthesisofhigherpolyglycerols
AT kuipersbonnywm caoasdropincolloidalcatalystsforthesynthesisofhigherpolyglycerols
AT kaiseranton caoasdropincolloidalcatalystsforthesynthesisofhigherpolyglycerols
AT bruijnincxpieterca caoasdropincolloidalcatalystsforthesynthesisofhigherpolyglycerols
AT weckhuysenbertm caoasdropincolloidalcatalystsforthesynthesisofhigherpolyglycerols