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CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols
Glycerol is an attractive renewable building block for the synthesis of polyglycerols, which find application in the cosmetic and pharmaceutical industries. The selective etherification of glycerol to higher oligomers was studied in the presence of CaO colloids and the data are compared with those o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464545/ https://www.ncbi.nlm.nih.gov/pubmed/25684403 http://dx.doi.org/10.1002/chem.201405906 |
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author | Kirby, Fiona Nieuwelink, Anne-Eva Kuipers, Bonny W M Kaiser, Anton Bruijnincx, Pieter C A Weckhuysen, Bert M |
author_facet | Kirby, Fiona Nieuwelink, Anne-Eva Kuipers, Bonny W M Kaiser, Anton Bruijnincx, Pieter C A Weckhuysen, Bert M |
author_sort | Kirby, Fiona |
collection | PubMed |
description | Glycerol is an attractive renewable building block for the synthesis of polyglycerols, which find application in the cosmetic and pharmaceutical industries. The selective etherification of glycerol to higher oligomers was studied in the presence of CaO colloids and the data are compared with those obtained from NaOH and CaO. The materials were prepared by dispersing CaO, CaCO(3), or Ca(OH)(2) onto a carbon nanofiber (CNF) support. Colloidal nanoparticles were subsequently dispensed from the CNF into the reaction mixture to give CaO colloids that have a higher activity than equimolar amounts of bulk CaO and NaOH. Optimization of the reaction conditions allowed us to obtain a product with Gardner color number <2, containing no acrolein and minimal cyclic byproducts. The differences in the CaO colloids originating from CNF and bulk CaO were probed using light scattering and conductivity measurements. The results confirmed that the higher activity of the colloids originating from CaO/CNF was due to their more rapid formation and smaller size compared with colloids from bulk CaO. We thus have developed a practical method for the synthesis of polyglycerols containing low amounts of Ca. |
format | Online Article Text |
id | pubmed-4464545 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | WILEY-VCH Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-44645452015-06-17 CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols Kirby, Fiona Nieuwelink, Anne-Eva Kuipers, Bonny W M Kaiser, Anton Bruijnincx, Pieter C A Weckhuysen, Bert M Chemistry Full Papers Glycerol is an attractive renewable building block for the synthesis of polyglycerols, which find application in the cosmetic and pharmaceutical industries. The selective etherification of glycerol to higher oligomers was studied in the presence of CaO colloids and the data are compared with those obtained from NaOH and CaO. The materials were prepared by dispersing CaO, CaCO(3), or Ca(OH)(2) onto a carbon nanofiber (CNF) support. Colloidal nanoparticles were subsequently dispensed from the CNF into the reaction mixture to give CaO colloids that have a higher activity than equimolar amounts of bulk CaO and NaOH. Optimization of the reaction conditions allowed us to obtain a product with Gardner color number <2, containing no acrolein and minimal cyclic byproducts. The differences in the CaO colloids originating from CNF and bulk CaO were probed using light scattering and conductivity measurements. The results confirmed that the higher activity of the colloids originating from CaO/CNF was due to their more rapid formation and smaller size compared with colloids from bulk CaO. We thus have developed a practical method for the synthesis of polyglycerols containing low amounts of Ca. WILEY-VCH Verlag 2015-03-23 2015-02-13 /pmc/articles/PMC4464545/ /pubmed/25684403 http://dx.doi.org/10.1002/chem.201405906 Text en © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the terms of the Creative Commons Attribution Non-Commercial NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Full Papers Kirby, Fiona Nieuwelink, Anne-Eva Kuipers, Bonny W M Kaiser, Anton Bruijnincx, Pieter C A Weckhuysen, Bert M CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols |
title | CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols |
title_full | CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols |
title_fullStr | CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols |
title_full_unstemmed | CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols |
title_short | CaO as Drop-In Colloidal Catalysts for the Synthesis of Higher Polyglycerols |
title_sort | cao as drop-in colloidal catalysts for the synthesis of higher polyglycerols |
topic | Full Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464545/ https://www.ncbi.nlm.nih.gov/pubmed/25684403 http://dx.doi.org/10.1002/chem.201405906 |
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