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Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains

BACKGROUND: Mouse models are useful for studying cigarette smoke (CS)-induced chronic pulmonary pathologies such as lung emphysema. To enhance translation of large-scale omics data from mechanistic studies into pathophysiological changes, we have developed computational tools based on reverse causal...

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Detalles Bibliográficos
Autores principales:	Cabanski, Maciej, Fields, Brett, Boue, Stephanie, Boukharov, Natalia, DeLeon, Hector, Dror, Natalie, Geertz, Marcel, Guedj, Emmanuel, Iskandar, Anita, Kogel, Ulrike, Merg, Celine, Peck, Michael J., Poussin, Carine, Schlage, Walter K., Talikka, Marja, Ivanov, Nikolai V., Hoeng, Julia, Peitsch, Manuel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Basel 2015
Materias:	Original Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464601/ https://www.ncbi.nlm.nih.gov/pubmed/25962837 http://dx.doi.org/10.1007/s00011-015-0820-2

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