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Antiproliferative Effect of Rottlerin on Sk-Mel-28 Melanoma Cells
Melanoma is the most aggressive and chemoresistant form of skin cancer. Mutated, constitutively active B-RAF is believed to play a crucial role, although the selective B-RAF inhibition has shown poor clinical success, since phenomena of resistance usually occur, likely arising from additional geneti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464680/ https://www.ncbi.nlm.nih.gov/pubmed/26161122 http://dx.doi.org/10.1155/2015/545838 |