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Effects of hypoxia inducible factor-1α on apoptotic inhibition and glucocorticoid receptor downregulation by dexamethasone in AtT-20 cells
BACKGROUND: Hypoxia inducible factor-1α (HIF-1α) is the central transcriptional regulator of hypoxic responses during the progression of pituitary adenomas. Although previous immunohistochemical studies revealed that HIF-1α is expressed in adreno-cortico-tropic-hormone (ACTH) pituitary adenomas, the...
Autores principales: | Zhang, Chenran, Qiang, Qiang, Jiang, Ying, Hu, Liuhua, Ding, Xuehua, Lu, Yicheng, Hu, Guohan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464719/ https://www.ncbi.nlm.nih.gov/pubmed/26002039 http://dx.doi.org/10.1186/s12902-015-0017-2 |
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