Curcumin prophylaxis mitigates the incidence of hypobaric hypoxia-induced altered ion channels expression and impaired tight junction proteins integrity in rat brain

BACKGROUND: The present study was proposed to elucidate the prophylactic role of curcumin in the prevention of hypoxia-induced cerebral edema (HACE). METHODS: Rats were exposed to simulated hypobaric hypoxia at 7620 m for 24 h at 25 ± 1 °C. Transvascular leakage, expression of transcriptional factor...

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Detalles Bibliográficos
Autores principales: Sarada, SKS, Titto, M, Himadri, P, Saumya, S, Vijayalakshmi, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464871/
https://www.ncbi.nlm.nih.gov/pubmed/26048285
http://dx.doi.org/10.1186/s12974-015-0326-4

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