Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis

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Several authors have confirmed that 27 to 38 % of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adoles...

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Detalles Bibliográficos
Autores principales: Ishida, Ko, Aota, Yoichi, Mitsugi, Naoto, Kono, Motonori, Higashi, Takayuki, Kawai, Takuya, Yamada, Katsutaka, Niimura, Takanori, Kaneko, Kanichiro, Tanabe, Hironori, Ito, Yohei, Katsuhata, Tomoyuki, Saito, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464881/
https://www.ncbi.nlm.nih.gov/pubmed/26075016
http://dx.doi.org/10.1186/s13013-015-0043-x
Descripción
Sumario:Several authors have confirmed that 27 to 38 % of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59 % of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients.

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