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Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis
Several authors have confirmed that 27 to 38 % of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adoles...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464881/ https://www.ncbi.nlm.nih.gov/pubmed/26075016 http://dx.doi.org/10.1186/s13013-015-0043-x |
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| author | Ishida, Ko Aota, Yoichi Mitsugi, Naoto Kono, Motonori Higashi, Takayuki Kawai, Takuya Yamada, Katsutaka Niimura, Takanori Kaneko, Kanichiro Tanabe, Hironori Ito, Yohei Katsuhata, Tomoyuki Saito, Tomoyuki |
| author_facet | Ishida, Ko Aota, Yoichi Mitsugi, Naoto Kono, Motonori Higashi, Takayuki Kawai, Takuya Yamada, Katsutaka Niimura, Takanori Kaneko, Kanichiro Tanabe, Hironori Ito, Yohei Katsuhata, Tomoyuki Saito, Tomoyuki |
| author_sort | Ishida, Ko |
| collection | PubMed |
| description | Several authors have confirmed that 27 to 38 % of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59 % of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients. |
| format | Online Article Text |
| id | pubmed-4464881 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-44648812015-06-14 Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis Ishida, Ko Aota, Yoichi Mitsugi, Naoto Kono, Motonori Higashi, Takayuki Kawai, Takuya Yamada, Katsutaka Niimura, Takanori Kaneko, Kanichiro Tanabe, Hironori Ito, Yohei Katsuhata, Tomoyuki Saito, Tomoyuki Scoliosis Research Several authors have confirmed that 27 to 38 % of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59 % of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients. BioMed Central 2015-06-12 /pmc/articles/PMC4464881/ /pubmed/26075016 http://dx.doi.org/10.1186/s13013-015-0043-x Text en © Ishida et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Research Ishida, Ko Aota, Yoichi Mitsugi, Naoto Kono, Motonori Higashi, Takayuki Kawai, Takuya Yamada, Katsutaka Niimura, Takanori Kaneko, Kanichiro Tanabe, Hironori Ito, Yohei Katsuhata, Tomoyuki Saito, Tomoyuki Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis |
| title | Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis |
| title_full | Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis |
| title_fullStr | Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis |
| title_full_unstemmed | Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis |
| title_short | Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis |
| title_sort | relationship between bone density and bone metabolism in adolescent idiopathic scoliosis |
| topic | Research |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464881/ https://www.ncbi.nlm.nih.gov/pubmed/26075016 http://dx.doi.org/10.1186/s13013-015-0043-x |
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