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Role of FNAC in the diagnosis of intraosseous jaw lesions

BACKGROUND: FNAC of intraosseous jaw lesions has not been widely utilized for diagnosis due to rarity and diversity of these lesions, limited experience and lack of well established cytological features. Aim of the study was to determine the role of FNAC in the diagnosis of intraosseous jaw swelling...

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Autores principales: Goyal, Surbhi, Sharma, Sonal, Kotru, Mrinalini, Gupta, Neelima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464915/
https://www.ncbi.nlm.nih.gov/pubmed/25662547
http://dx.doi.org/10.4317/medoral.20274
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author Goyal, Surbhi
Sharma, Sonal
Kotru, Mrinalini
Gupta, Neelima
author_facet Goyal, Surbhi
Sharma, Sonal
Kotru, Mrinalini
Gupta, Neelima
author_sort Goyal, Surbhi
collection PubMed
description BACKGROUND: FNAC of intraosseous jaw lesions has not been widely utilized for diagnosis due to rarity and diversity of these lesions, limited experience and lack of well established cytological features. Aim of the study was to determine the role of FNAC in the diagnosis of intraosseous jaw swellings. MATERIAL AND METHODS: 42 patients underwent FNAC over a period of 7 years (2007-2013), of which 37 (88.1%) aspirates were diagnostic. Histopathology correlation was available in 33 cases and diagnostic accuracy of FNAC was calculated. RESULTS: Lesions were categorized into inflammatory 3, cysts/hamartomas 15 and neoplasms 19. Mandibular and maxillary involvement was seen in 21 and 16 patients respectively. Of these, benign cysts and malignant lesions were commonest, accounting for 27% lesions (10 cases) each. One case of cystic ameloblastoma was misdiagnosed as odontogenic cyst on cytology. Overall, sensitivity and specificity of FNAC were 94.7% and 100% respectively with a diagnostic accuracy of 97.3%. Definitive categorization of giant cell lesions, fibro-osseous lesions, odontogenic tumors and cystic lesions was not feasible on FNAC. CONCLUSIONS: FNAC is a simple, safe and minimally invasive first line investigation which can render an accurate preoperative diagnosis of intraosseous jaw lesions, especially the malignant ones in the light of clinic-radiological correlation. Key words: Jaw swellings, intraosseous, FNAC.
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spelling pubmed-44649152015-06-16 Role of FNAC in the diagnosis of intraosseous jaw lesions Goyal, Surbhi Sharma, Sonal Kotru, Mrinalini Gupta, Neelima Med Oral Patol Oral Cir Bucal Research BACKGROUND: FNAC of intraosseous jaw lesions has not been widely utilized for diagnosis due to rarity and diversity of these lesions, limited experience and lack of well established cytological features. Aim of the study was to determine the role of FNAC in the diagnosis of intraosseous jaw swellings. MATERIAL AND METHODS: 42 patients underwent FNAC over a period of 7 years (2007-2013), of which 37 (88.1%) aspirates were diagnostic. Histopathology correlation was available in 33 cases and diagnostic accuracy of FNAC was calculated. RESULTS: Lesions were categorized into inflammatory 3, cysts/hamartomas 15 and neoplasms 19. Mandibular and maxillary involvement was seen in 21 and 16 patients respectively. Of these, benign cysts and malignant lesions were commonest, accounting for 27% lesions (10 cases) each. One case of cystic ameloblastoma was misdiagnosed as odontogenic cyst on cytology. Overall, sensitivity and specificity of FNAC were 94.7% and 100% respectively with a diagnostic accuracy of 97.3%. Definitive categorization of giant cell lesions, fibro-osseous lesions, odontogenic tumors and cystic lesions was not feasible on FNAC. CONCLUSIONS: FNAC is a simple, safe and minimally invasive first line investigation which can render an accurate preoperative diagnosis of intraosseous jaw lesions, especially the malignant ones in the light of clinic-radiological correlation. Key words: Jaw swellings, intraosseous, FNAC. Medicina Oral S.L. 2015-05 2015-02-07 /pmc/articles/PMC4464915/ /pubmed/25662547 http://dx.doi.org/10.4317/medoral.20274 Text en Copyright: © 2015 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Goyal, Surbhi
Sharma, Sonal
Kotru, Mrinalini
Gupta, Neelima
Role of FNAC in the diagnosis of intraosseous jaw lesions
title Role of FNAC in the diagnosis of intraosseous jaw lesions
title_full Role of FNAC in the diagnosis of intraosseous jaw lesions
title_fullStr Role of FNAC in the diagnosis of intraosseous jaw lesions
title_full_unstemmed Role of FNAC in the diagnosis of intraosseous jaw lesions
title_short Role of FNAC in the diagnosis of intraosseous jaw lesions
title_sort role of fnac in the diagnosis of intraosseous jaw lesions
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464915/
https://www.ncbi.nlm.nih.gov/pubmed/25662547
http://dx.doi.org/10.4317/medoral.20274
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