Chronic NF-κB blockade improves renal angiotensin II type 1 receptor functions and reduces blood pressure in Zucker diabetic rats

BACKGROUND: Both angiotensin II type 1 receptor (AT(1)R) and nuclear factor-kappa B (NF-κB) play significant roles in the pathogenesis of hypertension and type 2 diabetes. However, the role of NF-κB in perpetuating renal AT(1) receptors dysfunction remains unclear. The aim of the present study to de...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Hao, Wang, Xinquan, Wang, Jialiang, Chen, Caiyu, Wang, Na, Xu, Zaicheng, Chen, Shuo, Zeng, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465496/
https://www.ncbi.nlm.nih.gov/pubmed/26055622
http://dx.doi.org/10.1186/s12933-015-0239-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465496/
https://www.ncbi.nlm.nih.gov/pubmed/26055622
http://dx.doi.org/10.1186/s12933-015-0239-7

Ejemplares similares