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Chronic NF-κB blockade improves renal angiotensin II type 1 receptor functions and reduces blood pressure in Zucker diabetic rats

BACKGROUND: Both angiotensin II type 1 receptor (AT(1)R) and nuclear factor-kappa B (NF-κB) play significant roles in the pathogenesis of hypertension and type 2 diabetes. However, the role of NF-κB in perpetuating renal AT(1) receptors dysfunction remains unclear. The aim of the present study to de...

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Detalles Bibliográficos
Autores principales:	Luo, Hao, Wang, Xinquan, Wang, Jialiang, Chen, Caiyu, Wang, Na, Xu, Zaicheng, Chen, Shuo, Zeng, Chunyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465496/ https://www.ncbi.nlm.nih.gov/pubmed/26055622 http://dx.doi.org/10.1186/s12933-015-0239-7

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