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Plasma Proteomic Profiling in Hereditary Breast Cancer Reveals a BRCA1-Specific Signature: Diagnostic and Functional Implications

BACKGROUND: Breast cancer (BC) is a leading cause of death among women. Among the major risk factors, an important role is played by familial history of BC. Germ-line mutations in BRCA1/2 genes account for most of the hereditary breast and/or ovarian cancers. Gene expression profiling studies have d...

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Detalles Bibliográficos
Autores principales: Scumaci, Domenica, Tammè, Laura, Fiumara, Claudia Vincenza, Pappaianni, Giusi, Concolino, Antonio, Leone, Emanuela, Faniello, Maria Concetta, Quaresima, Barbara, Ricevuto, Enrico, Costanzo, Francesco Saverio, Cuda, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465499/
https://www.ncbi.nlm.nih.gov/pubmed/26061043
http://dx.doi.org/10.1371/journal.pone.0129762