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Oral Wild-Type Salmonella Typhi Challenge Induces Activation of Circulating Monocytes and Dendritic Cells in Individuals Who Develop Typhoid Disease

A new human oral challenge model with wild-type Salmonella Typhi (S. Typhi) was recently developed. In this model, ingestion of 104 CFU of Salmonella resulted in 65% of subjects developing typhoid fever (referred here as typhoid diagnosis -TD-) 5–10 days post-challenge. TD criteria included meeting...

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Detalles Bibliográficos
Autores principales:	Toapanta, Franklin R., Bernal, Paula J., Fresnay, Stephanie, Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Dougan, Gordon, Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465829/ https://www.ncbi.nlm.nih.gov/pubmed/26065687 http://dx.doi.org/10.1371/journal.pntd.0003837

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