Cooperative DNA Recognition Modulated by an Interplay between Protein-Protein Interactions and DNA-Mediated Allostery

Highly specific transcriptional regulation depends on the cooperative association of transcription factors into enhanceosomes. Usually, their DNA-binding cooperativity originates from either direct interactions or DNA-mediated allostery. Here, we performed unbiased molecular simulations followed by...

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Detalles Bibliográficos
Autores principales: Merino, Felipe, Bouvier, Benjamin, Cojocaru, Vlad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465831/
https://www.ncbi.nlm.nih.gov/pubmed/26067358
http://dx.doi.org/10.1371/journal.pcbi.1004287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465831/
https://www.ncbi.nlm.nih.gov/pubmed/26067358
http://dx.doi.org/10.1371/journal.pcbi.1004287

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