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Cooperative DNA Recognition Modulated by an Interplay between Protein-Protein Interactions and DNA-Mediated Allostery
Highly specific transcriptional regulation depends on the cooperative association of transcription factors into enhanceosomes. Usually, their DNA-binding cooperativity originates from either direct interactions or DNA-mediated allostery. Here, we performed unbiased molecular simulations followed by...
Autores principales: | Merino, Felipe, Bouvier, Benjamin, Cojocaru, Vlad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465831/ https://www.ncbi.nlm.nih.gov/pubmed/26067358 http://dx.doi.org/10.1371/journal.pcbi.1004287 |
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