Cargando…
Zinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase
OBJECTIVE: Evidence from mouse models suggests that zinc-α2-glycoprotein (ZAG) is a novel anti-obesity adipokine. In humans, however, data are controversial and its physiological role in adipose tissue (AT) remains unknown. Here we explored the molecular mechanisms by which ZAG regulates carbohydrat...
Autores principales: | Ceperuelo-Mallafré, Victòria, Ejarque, Miriam, Duran, Xavier, Pachón, Gisela, Vázquez-Carballo, Ana, Roche, Kelly, Núñez-Roa, Catalina, Garrido-Sánchez, Lourdes, Tinahones, Francisco J., Vendrell, Joan, Fernández-Veledo, Sonia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465909/ https://www.ncbi.nlm.nih.gov/pubmed/26068931 http://dx.doi.org/10.1371/journal.pone.0129644 |
Ejemplares similares
-
Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis
por: Ejarque, Miriam, et al.
Publicado: (2017) -
Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans
por: Ceperuelo-Mallafré, Victòria, et al.
Publicado: (2015) -
Survivin drives tumor-associated macrophage reprogramming: a novel mechanism with potential impact for obesity
por: Benaiges, E., et al.
Publicado: (2021) -
Effects of stem cells from inducible brown adipose tissue on diet-induced obesity in mice
por: Calvo, Enrique, et al.
Publicado: (2021) -
Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells
por: Ejarque, Miriam, et al.
Publicado: (2018)