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Rotation survival forest for right censored data
Recently, survival ensembles have found more and more applications in biological and medical research when censored time-to-event data are often confronted. In this research, we investigate the plausibility of extending a rotation forest, originally proposed for classification purpose, to survival a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465950/ https://www.ncbi.nlm.nih.gov/pubmed/26082863 http://dx.doi.org/10.7717/peerj.1009 |
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author | Zhou, Lifeng Xu, Qingsong Wang, Hong |
author_facet | Zhou, Lifeng Xu, Qingsong Wang, Hong |
author_sort | Zhou, Lifeng |
collection | PubMed |
description | Recently, survival ensembles have found more and more applications in biological and medical research when censored time-to-event data are often confronted. In this research, we investigate the plausibility of extending a rotation forest, originally proposed for classification purpose, to survival analysis. Supported by the proper statistical analysis, we show that rotation survival forests are able to outperform the state-of-art survival ensembles on right censored data. We also provide a C-index based variable importance measure for evaluating covariates in censored survival data. |
format | Online Article Text |
id | pubmed-4465950 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | PeerJ Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-44659502015-06-16 Rotation survival forest for right censored data Zhou, Lifeng Xu, Qingsong Wang, Hong PeerJ Bioinformatics Recently, survival ensembles have found more and more applications in biological and medical research when censored time-to-event data are often confronted. In this research, we investigate the plausibility of extending a rotation forest, originally proposed for classification purpose, to survival analysis. Supported by the proper statistical analysis, we show that rotation survival forests are able to outperform the state-of-art survival ensembles on right censored data. We also provide a C-index based variable importance measure for evaluating covariates in censored survival data. PeerJ Inc. 2015-06-11 /pmc/articles/PMC4465950/ /pubmed/26082863 http://dx.doi.org/10.7717/peerj.1009 Text en © 2015 Zhou et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. |
spellingShingle | Bioinformatics Zhou, Lifeng Xu, Qingsong Wang, Hong Rotation survival forest for right censored data |
title | Rotation survival forest for right censored data |
title_full | Rotation survival forest for right censored data |
title_fullStr | Rotation survival forest for right censored data |
title_full_unstemmed | Rotation survival forest for right censored data |
title_short | Rotation survival forest for right censored data |
title_sort | rotation survival forest for right censored data |
topic | Bioinformatics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465950/ https://www.ncbi.nlm.nih.gov/pubmed/26082863 http://dx.doi.org/10.7717/peerj.1009 |
work_keys_str_mv | AT zhoulifeng rotationsurvivalforestforrightcensoreddata AT xuqingsong rotationsurvivalforestforrightcensoreddata AT wanghong rotationsurvivalforestforrightcensoreddata |