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Rotation survival forest for right censored data

Recently, survival ensembles have found more and more applications in biological and medical research when censored time-to-event data are often confronted. In this research, we investigate the plausibility of extending a rotation forest, originally proposed for classification purpose, to survival a...

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Detalles Bibliográficos
Autores principales: Zhou, Lifeng, Xu, Qingsong, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465950/
https://www.ncbi.nlm.nih.gov/pubmed/26082863
http://dx.doi.org/10.7717/peerj.1009
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author Zhou, Lifeng
Xu, Qingsong
Wang, Hong
author_facet Zhou, Lifeng
Xu, Qingsong
Wang, Hong
author_sort Zhou, Lifeng
collection PubMed
description Recently, survival ensembles have found more and more applications in biological and medical research when censored time-to-event data are often confronted. In this research, we investigate the plausibility of extending a rotation forest, originally proposed for classification purpose, to survival analysis. Supported by the proper statistical analysis, we show that rotation survival forests are able to outperform the state-of-art survival ensembles on right censored data. We also provide a C-index based variable importance measure for evaluating covariates in censored survival data.
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spelling pubmed-44659502015-06-16 Rotation survival forest for right censored data Zhou, Lifeng Xu, Qingsong Wang, Hong PeerJ Bioinformatics Recently, survival ensembles have found more and more applications in biological and medical research when censored time-to-event data are often confronted. In this research, we investigate the plausibility of extending a rotation forest, originally proposed for classification purpose, to survival analysis. Supported by the proper statistical analysis, we show that rotation survival forests are able to outperform the state-of-art survival ensembles on right censored data. We also provide a C-index based variable importance measure for evaluating covariates in censored survival data. PeerJ Inc. 2015-06-11 /pmc/articles/PMC4465950/ /pubmed/26082863 http://dx.doi.org/10.7717/peerj.1009 Text en © 2015 Zhou et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Bioinformatics
Zhou, Lifeng
Xu, Qingsong
Wang, Hong
Rotation survival forest for right censored data
title Rotation survival forest for right censored data
title_full Rotation survival forest for right censored data
title_fullStr Rotation survival forest for right censored data
title_full_unstemmed Rotation survival forest for right censored data
title_short Rotation survival forest for right censored data
title_sort rotation survival forest for right censored data
topic Bioinformatics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465950/
https://www.ncbi.nlm.nih.gov/pubmed/26082863
http://dx.doi.org/10.7717/peerj.1009
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