Optical Imaging of Paramagnetic Bead-DNA Aggregation Inhibition Allows for Low Copy Number Detection of Infectious Pathogens

DNA-paramagnetic silica bead aggregation in a rotating magnetic field facilitates the quantification of DNA with femtogram sensitivity, but yields no sequence-specific information. Here we provide an original description of aggregation inhibition for the detection of DNA and RNA in a sequence-specif...

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Detalles Bibliográficos
Autores principales: DuVall, Jacquelyn A., Borba, Juliane C., Shafagati, Nazly, Luzader, Deborah, Shukla, Nishant, Li, Jingyi, Kehn-Hall, Kylene, Kendall, Melissa M., Feldman, Sanford H., Landers, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466016/
https://www.ncbi.nlm.nih.gov/pubmed/26068926
http://dx.doi.org/10.1371/journal.pone.0129830

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