Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications

Nanomaterials, including metal-based nanoparticles, are used for various biological and medical applications. However, metals affect immune functions in many animal species including humans. Different physical and chemical properties induce different cellular responses, such as cellular uptake and i...

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Detalles Bibliográficos
Autores principales: Luo, Yueh-Hsia, Chang, Louis W., Lin, Pinpin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466342/
https://www.ncbi.nlm.nih.gov/pubmed/26125021
http://dx.doi.org/10.1155/2015/143720
Descripción
Sumario:Nanomaterials, including metal-based nanoparticles, are used for various biological and medical applications. However, metals affect immune functions in many animal species including humans. Different physical and chemical properties induce different cellular responses, such as cellular uptake and intracellular biodistribution, leading to the different immune responses. The goals of this review are to summarize and discuss the innate and adaptive immune responses triggered by metal-based nanoparticles in a variety of immune system models.

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