Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications

Nanomaterials, including metal-based nanoparticles, are used for various biological and medical applications. However, metals affect immune functions in many animal species including humans. Different physical and chemical properties induce different cellular responses, such as cellular uptake and i...

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Detalles Bibliográficos
Autores principales: Luo, Yueh-Hsia, Chang, Louis W., Lin, Pinpin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466342/
https://www.ncbi.nlm.nih.gov/pubmed/26125021
http://dx.doi.org/10.1155/2015/143720
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author Luo, Yueh-Hsia
Chang, Louis W.
Lin, Pinpin
author_facet Luo, Yueh-Hsia
Chang, Louis W.
Lin, Pinpin
author_sort Luo, Yueh-Hsia
collection PubMed
description Nanomaterials, including metal-based nanoparticles, are used for various biological and medical applications. However, metals affect immune functions in many animal species including humans. Different physical and chemical properties induce different cellular responses, such as cellular uptake and intracellular biodistribution, leading to the different immune responses. The goals of this review are to summarize and discuss the innate and adaptive immune responses triggered by metal-based nanoparticles in a variety of immune system models.
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spelling pubmed-44663422015-06-29 Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications Luo, Yueh-Hsia Chang, Louis W. Lin, Pinpin Biomed Res Int Review Article Nanomaterials, including metal-based nanoparticles, are used for various biological and medical applications. However, metals affect immune functions in many animal species including humans. Different physical and chemical properties induce different cellular responses, such as cellular uptake and intracellular biodistribution, leading to the different immune responses. The goals of this review are to summarize and discuss the innate and adaptive immune responses triggered by metal-based nanoparticles in a variety of immune system models. Hindawi Publishing Corporation 2015 2015-06-01 /pmc/articles/PMC4466342/ /pubmed/26125021 http://dx.doi.org/10.1155/2015/143720 Text en Copyright © 2015 Yueh-Hsia Luo et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Luo, Yueh-Hsia
Chang, Louis W.
Lin, Pinpin
Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications
title Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications
title_full Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications
title_fullStr Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications
title_full_unstemmed Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications
title_short Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications
title_sort metal-based nanoparticles and the immune system: activation, inflammation, and potential applications
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466342/
https://www.ncbi.nlm.nih.gov/pubmed/26125021
http://dx.doi.org/10.1155/2015/143720
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