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Progression and Transformation of Clonally Heterogeneous B-cell Lymphoma

Indolent B- cell non-Hodgkin lymphoma can transform into aggressive lymphoma. We extend our prior mathematical model to analyze and predict transformation. To provide additional confidence in our model, we compare it with SCID mouse data for combination therapy of Diffuse Large B-cell Lymphoma, an a...

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Detalles Bibliográficos
Autores principales: Weiss, Robert F., Smith, Mitchell R., Miller, Merlin G., Cronin, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466348/
https://www.ncbi.nlm.nih.gov/pubmed/26068800
http://dx.doi.org/10.1371/journal.pone.0130590