Improvement of Renal Function by Long-Term Sustained Eculizumab Treatment in a Patient with Paroxysmal Nocturnal Hemoglobinuria

Chronic kidney disease (CKD) is one of the major manifestations of paroxysmal nocturnal hemoglobinuria (PNH). CKD in PNH is induced mainly by intravascular hemolysis of PNH-affected red blood cells (RBC) missing the glycosylphosphatidylinositol-anchored proteins with complement-regulatory activities...

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Detalles Bibliográficos
Autores principales: Ninomiya, Haruhiko, Obara, Naoshi, Niiori-Onishi, Akiko, Yokoyama, Yasuhisa, Sakata-Yanagimoto, Mamiko, Hasegawa, Yuichi, Chiba, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466353/
https://www.ncbi.nlm.nih.gov/pubmed/26124968
http://dx.doi.org/10.1155/2015/673195

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