The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes

In recent years, the ubiquitin-editing enzyme A20 has been shown to control a large set of molecular pathways involved in the regulation of protective as well as self-directed immune responses. Here, we assess the current and putative roles of A20 in inflammatory, vascular and degenerative diseases...

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Autores principales: Abbasi, Asghar, Forsberg, Kirsi, Bischof, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466442/
https://www.ncbi.nlm.nih.gov/pubmed/26124703
http://dx.doi.org/10.3389/fnmol.2015.00021
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author Abbasi, Asghar
Forsberg, Kirsi
Bischof, Felix
author_facet Abbasi, Asghar
Forsberg, Kirsi
Bischof, Felix
author_sort Abbasi, Asghar
collection PubMed
description In recent years, the ubiquitin-editing enzyme A20 has been shown to control a large set of molecular pathways involved in the regulation of protective as well as self-directed immune responses. Here, we assess the current and putative roles of A20 in inflammatory, vascular and degenerative diseases of the central nervous system and explore future directions of research.
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spelling pubmed-44664422015-06-29 The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes Abbasi, Asghar Forsberg, Kirsi Bischof, Felix Front Mol Neurosci Neuroscience In recent years, the ubiquitin-editing enzyme A20 has been shown to control a large set of molecular pathways involved in the regulation of protective as well as self-directed immune responses. Here, we assess the current and putative roles of A20 in inflammatory, vascular and degenerative diseases of the central nervous system and explore future directions of research. Frontiers Media S.A. 2015-06-15 /pmc/articles/PMC4466442/ /pubmed/26124703 http://dx.doi.org/10.3389/fnmol.2015.00021 Text en Copyright © 2015 Abbasi, Forsberg and Bischof. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Abbasi, Asghar
Forsberg, Kirsi
Bischof, Felix
The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes
title The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes
title_full The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes
title_fullStr The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes
title_full_unstemmed The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes
title_short The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes
title_sort role of the ubiquitin-editing enzyme a20 in diseases of the central nervous system and other pathological processes
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466442/
https://www.ncbi.nlm.nih.gov/pubmed/26124703
http://dx.doi.org/10.3389/fnmol.2015.00021
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