Valproate Attenuates 25-kDa C-Terminal Fragment of TDP-43-Induced Neuronal Toxicity via Suppressing Endoplasmic Reticulum Stress and Activating Autophagy

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disease. To date, there is no any effective pharmacological treatment for improving patients' symptoms and quality of life. Rapidly emerging evidence suggests that C-terminal fragments (CTFs) of TAR DNA-binding protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xuejing, Ma, Mingming, Teng, Junfang, Che, Xiangqian, Zhang, Wenwen, Feng, Shuman, Zhou, Shuang, Zhang, Ying, Wu, Erxi, Ding, Xuebing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466456/
https://www.ncbi.nlm.nih.gov/pubmed/26078717
http://dx.doi.org/10.7150/ijbs.11880

Ejemplares similares

Ejemplares similares