Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular

Staphylococcus aureus infections are a growing health burden worldwide, and paramount to this bacterium’s pathogenesis is the production of virulence factors, including pore-forming leukotoxins. Leukocidin A/B (LukAB) is a recently discovered toxin that kills primary human phagocytes, though the und...

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Detalles Bibliográficos
Autores principales: Melehani, Jason H., James, David B. A., DuMont, Ashley L., Torres, Victor J., Duncan, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466499/
https://www.ncbi.nlm.nih.gov/pubmed/26069969
http://dx.doi.org/10.1371/journal.ppat.1004970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466499/
https://www.ncbi.nlm.nih.gov/pubmed/26069969
http://dx.doi.org/10.1371/journal.ppat.1004970

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