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Prmt5 is required for germ cell survival during spermatogenesis in mice

During germ cell development, epigenetic modifications undergo extensive remodeling. Abnormal epigenetic modifications usually result in germ cell loss and reproductive defect. Prmt5 (Protein arginine methyltransferase 5) encodes a protein arginine methyltransferase which has been demonstrated to pl...

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Detalles Bibliográficos
Autores principales: Wang, Yanbo, Zhu, Tianxiang, Li, Qiuling, Liu, Chunyi, Han, Feng, Chen, Min, Zhang, Lianjun, Cui, Xiuhong, Qin, Yan, Bao, Shilai, Gao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466585/
https://www.ncbi.nlm.nih.gov/pubmed/26072710
http://dx.doi.org/10.1038/srep11031