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P-selectin-mediated platelet adhesion promotes tumor growth
Blood platelets foster carcinogenesis. We found that platelets are accumulated in human tumors. P-selectin deficiency and soluble P-selectin abolish platelet deposition within tumors, decreasing secretion of vascular endothelial growth factor and angiogenesis, thereby suppressing tumor growth. Bindi...
Autores principales: | Qi, Cuiling, Wei, Bo, Zhou, Weijie, Yang, Yang, Li, Bin, Guo, Simei, Li, Jialin, Ye, Jie, Li, Jiangchao, Zhang, Qianqian, Lan, Tian, He, Xiaodong, Cao, Liu, Zhou, Jia, Geng, Jianguo, Wang, Lijing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466636/ https://www.ncbi.nlm.nih.gov/pubmed/25762641 |
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