Cargando…
Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrin–NF-κB–HIF-1α pathway
There is increasing evidence to suggest that hepatocellular carcinomas (HCCs) are sustained by a distinct subpopulation of self-renewing cells known as cancer stem cells. However, the precise signals required for maintenance of stemness-like properties of these cells are yet to be elucidated. Here,...
Autores principales: | Cao, Lei, Fan, Xiaoyu, Jing, Wei, Liang, Yingchao, Chen, Rui, Liu, Yingying, Zhu, Minhui, Jia, Rongjie, Wang, Hao, Zhang, Xueguang, Zhang, Yanyun, Zhou, Xuyu, Zhao, Jian, Guo, Yajun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466639/ https://www.ncbi.nlm.nih.gov/pubmed/25749383 |
Ejemplares similares
-
Osteopontin facilitates tumor metastasis by regulating epithelial–mesenchymal plasticity
por: Jia, Rongjie, et al.
Publicado: (2016) -
Association between the Hypomethylation of Osteopontin and Integrin β3 Promoters and Vascular Smooth Muscle Cell Phenotype Switching in Great Saphenous Varicose Veins
por: Jiang, Han, et al.
Publicado: (2014) -
Osteopontin and integrin are involved in cholesterol gallstone formation
por: Yang, Lin, et al.
Publicado: (2012) -
Osteopontin–integrin engagement induces HIF-1α–TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer
por: Fan, Chi-Shuan, et al.
Publicado: (2017) -
Temporal regulation of HIF-1 and NF-κB in hypoxic hepatocarcinoma cells
por: Jiang, Yuan, et al.
Publicado: (2015)