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The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1

The mitotic centromere-associated kinesin (MCAK), a potent microtubule depolymerase, is involved in regulating microtubule dynamics. The activity and subcellular localization of MCAK are tightly regulated by key mitotic kinases, such as Polo-like kinase 1 (Plk1) by phosphorylating multiple residues...

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Detalles Bibliográficos
Autores principales: Ritter, Andreas, Sanhaji, Mourad, Steinhäuser, Kerstin, Roth, Susanne, Louwen, Frank, Yuan, Juping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466640/
https://www.ncbi.nlm.nih.gov/pubmed/25504441

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