Cbl-b inhibits P-gp transporter function by preventing its translocation into caveolae in multiple drug-resistant gastric and breast cancers

The transport function of P-glycoprotein (P-gp) requires its efficient localization to caveolae, a subset of lipid rafts, and disruption of caveolae suppresses P-gp transport function. However, the regulatory molecules involved in the translocation of P-gp into caveolae remain unknown. In the presen...

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Detalles Bibliográficos
Autores principales: Zhang, Ye, Qu, Xiujuan, Teng, Yuee, Li, Zhi, Xu, Ling, Liu, Jing, Ma, Yanju, Fan, Yibo, Li, Ce, Liu, Shizhou, Wang, Zhenning, Hu, Xuejun, Zhang, Jingdong, Liu, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466646/
https://www.ncbi.nlm.nih.gov/pubmed/25788263

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