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Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo

In development of amphibians and flies, gene amplification is one of mechanisms to increase gene expression. In mammalian cells, gene amplification seems to be restricted to tumorigenesis and acquiring of drug-resistance in cancer cells. Here, we report a complex gene amplification pattern in mouse...

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Detalles Bibliográficos
Autores principales: Fischer, Ulrike, Backes, Christina, Raslan, Abdulrahman, Keller, Andreas, Meier, Carola, Meese, Eckart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466667/
https://www.ncbi.nlm.nih.gov/pubmed/25760141

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