Multiple mechanisms of MYCN dysregulation in Wilms tumour

Genomic gain of the proto-oncogene transcription factor gene MYCN is associated with poor prognosis in several childhood cancers. Here we present a comprehensive copy number analysis of MYCN in Wilms tumour (WT), demonstrating that gain of this gene is associated with anaplasia and with poorer relap...

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Detalles Bibliográficos
Autores principales: Williams, Richard D., Chagtai, Tasnim, Alcaide-German, Marisa, Apps, John, Wegert, Jenny, Popov, Sergey, Vujanic, Gordan, van Tinteren, Harm, van den Heuvel-Eibrink, Marry M., Kool, Marcel, de Kraker, Jan, Gisselsson, David, Graf, Norbert, Gessler, Manfred, Pritchard-Jones, Kathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466681/
https://www.ncbi.nlm.nih.gov/pubmed/25749049

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