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In vitro model for lytic replication, latency, and transformation of an oncogenic alphaherpesvirus

Marek’s disease virus (MDV) is an alphaherpesvirus that causes deadly T-cell lymphomas in chickens and serves as a natural small animal model for virus-induced tumor formation. In vivo, MDV lytically replicates in B cells that transfer the virus to T cells in which the virus establishes latency. MDV...

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Detalles Bibliográficos
Autores principales: Schermuly, Julia, Greco, Annachiara, Härtle, Sonja, Osterrieder, Nikolaus, Kaufer, Benedikt B., Kaspers, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466724/
https://www.ncbi.nlm.nih.gov/pubmed/26039998
http://dx.doi.org/10.1073/pnas.1424420112