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Ultrasound-Guided Pulsed Radiofrequency for Carpal Tunnel Syndrome: A Single-Blinded Randomized Controlled Study

OBJECTIVE: We assessed the therapeutic efficiency of ultrasound-guided pulsed radiofrequency (PRF) treatment of the median nerve in patients with carpal tunnel syndrome (CTS). METHODS: We conducted a prospective, randomized, controlled, single-blinded study. Forty-four patients with CTS were randomi...

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Detalles Bibliográficos
Autores principales: Chen, Liang-Cheng, Ho, Cheng-Wen, Sun, Chia-Hung, Lee, Jiunn-Tay, Li, Tsung-Ying, Shih, Feng-Mei, Wu, Yung-Tsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466776/
https://www.ncbi.nlm.nih.gov/pubmed/26067628
http://dx.doi.org/10.1371/journal.pone.0129918
Descripción
Sumario:OBJECTIVE: We assessed the therapeutic efficiency of ultrasound-guided pulsed radiofrequency (PRF) treatment of the median nerve in patients with carpal tunnel syndrome (CTS). METHODS: We conducted a prospective, randomized, controlled, single-blinded study. Forty-four patients with CTS were randomized into intervention or control groups. Patients in the intervention group were treated with PRF and night splint, and the control group was prescribed night splint alone. Primary outcome was the onset time of significant pain relief assessed using the visual analog scale (VAS), and secondary outcomes included evaluation of the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) results, cross-sectional area (CSA) of the median nerve, sensory nerve conduction velocity (SNCV) of the median nerve, and finger pinch strength. All outcome measurements were performed at 1, 4, 8, and 12 weeks after treatment. RESULTS: Thirty-six patients completed the study. The onset time of pain relief in the intervention group was significantly shorter (median onset time of 2 days vs. 14 days; hazard ratio = 7.37; 95% CI, 3.04–17.87) compared to the control group (p < 0.001). Significant improvement in VAS and BCTQ scores (p < 0.05) was detected in the intervention group at all follow-up periods compared to the controls (except for the severity subscale of BCTQ at week 1). Ultrasound-guided PRF treatment resulted in a lower VAS score and stronger finger pinch compared to the control group over the entire study. CONCLUSIONS: Our study shows that ultrasound-guided PRF serves as a better approach for pain relief in patients with CTS. TRIAL REGISTRATION: ClinicalTrials.gov NCT02217293