Exploring the Use of a Guanine-Rich Catalytic DNA for Sulfoxide Preparation

A guanine-rich DNA oligonucleotide complexed with hemin was used to catalyze controlled oxygen transfer reactions to different sulfides for sulfoxide preparation in the presence of H(2)O(2). Comparable activities were obtained when using fully modified L-DNA. In addition, oligonucleotide immobilizat...

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Detalles Bibliográficos
Autores principales: Dellafiore, María A., Montserrat, Javier M., Iribarren, Adolfo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466802/
https://www.ncbi.nlm.nih.gov/pubmed/26066510
http://dx.doi.org/10.1371/journal.pone.0129695
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author Dellafiore, María A.
Montserrat, Javier M.
Iribarren, Adolfo M.
author_facet Dellafiore, María A.
Montserrat, Javier M.
Iribarren, Adolfo M.
author_sort Dellafiore, María A.
collection PubMed
description A guanine-rich DNA oligonucleotide complexed with hemin was used to catalyze controlled oxygen transfer reactions to different sulfides for sulfoxide preparation in the presence of H(2)O(2). Comparable activities were obtained when using fully modified L-DNA. In addition, oligonucleotide immobilization led to an active catalyst which could be successfully recovered and reused without loss of activity.
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spelling pubmed-44668022015-06-22 Exploring the Use of a Guanine-Rich Catalytic DNA for Sulfoxide Preparation Dellafiore, María A. Montserrat, Javier M. Iribarren, Adolfo M. PLoS One Research Article A guanine-rich DNA oligonucleotide complexed with hemin was used to catalyze controlled oxygen transfer reactions to different sulfides for sulfoxide preparation in the presence of H(2)O(2). Comparable activities were obtained when using fully modified L-DNA. In addition, oligonucleotide immobilization led to an active catalyst which could be successfully recovered and reused without loss of activity. Public Library of Science 2015-06-12 /pmc/articles/PMC4466802/ /pubmed/26066510 http://dx.doi.org/10.1371/journal.pone.0129695 Text en © 2015 Dellafiore et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Dellafiore, María A.
Montserrat, Javier M.
Iribarren, Adolfo M.
Exploring the Use of a Guanine-Rich Catalytic DNA for Sulfoxide Preparation
title Exploring the Use of a Guanine-Rich Catalytic DNA for Sulfoxide Preparation
title_full Exploring the Use of a Guanine-Rich Catalytic DNA for Sulfoxide Preparation
title_fullStr Exploring the Use of a Guanine-Rich Catalytic DNA for Sulfoxide Preparation
title_full_unstemmed Exploring the Use of a Guanine-Rich Catalytic DNA for Sulfoxide Preparation
title_short Exploring the Use of a Guanine-Rich Catalytic DNA for Sulfoxide Preparation
title_sort exploring the use of a guanine-rich catalytic dna for sulfoxide preparation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466802/
https://www.ncbi.nlm.nih.gov/pubmed/26066510
http://dx.doi.org/10.1371/journal.pone.0129695
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