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Morphine compromises bronchial epithelial TLR2/IL17R signaling crosstalk, necessary for lung IL17 homeostasis

Opportunistic lung infection and inflammation is a hallmark of chronic recreational/clinical use of morphine. We show that early induction of IL17 from the bronchial epithelium, following pathogenic encounter is a protective response, which contributes to pathogenic clearance and currently attribute...

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Detalles Bibliográficos
Autores principales: Banerjee, Santanu, Ninkovic, Jana, Meng, Jingjing, Sharma, Umakant, Ma, Jing, Charboneau, Richard, Roy, Sabita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466887/
https://www.ncbi.nlm.nih.gov/pubmed/26072707
http://dx.doi.org/10.1038/srep11384