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Aging-related rotenone-induced neurochemical and behavioral deficits: role of SIRT2 and redox imbalance, and neuroprotection by AK-7

Aging is one of the strongest risk factors for Parkinson’s disease (PD). SIRT2 has been implicated in the aging process. It is pertinent to investigate the role of SIRT2 in aging-related dopaminergic neurotoxicity and to develop effective therapeutic strategies for PD through the use of aging animal...

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Detalles Bibliográficos
Autores principales:	Wang, Xijin, Guan, Qiang, Wang, Meihua, Yang, Liu, Bai, Jie, Yan, Zhiqiang, Zhang, Yuhong, Liu, Zhenguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466888/ https://www.ncbi.nlm.nih.gov/pubmed/26089639 http://dx.doi.org/10.2147/DDDT.S81539

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