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The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor
Glioblastoma (GBM) is an infiltrative tumor that is difficult to eradicate. Treating GBM with mesenchymal stem cells (MSCs) that have been modified with the HSV-Tk suicide gene has brought significant advances mainly because MSCs are chemoattracted to GBM and kill tumor cells via a bystander effect....
Autores principales: | de Melo, Suely Maymone, Bittencourt, Simone, Ferrazoli, Enéas Galdini, da Silva, Clivandir Severino, da Cunha, Flavia Franco, da Silva, Flavia Helena, Stilhano, Roberta Sessa, Denapoli, Priscila Martins Andrade, Zanetti, Bianca Ferrarini, Martin, Priscila Keiko Matsumoto, Silva, Leonardo Martins, dos Santos, Adara Aurea, Baptista, Leandra Santos, Longo, Beatriz Monteiro, Han, Sang Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467037/ https://www.ncbi.nlm.nih.gov/pubmed/26067671 http://dx.doi.org/10.1371/journal.pone.0128922 |
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