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Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors

In addition to local cytotoxic activity, radiotherapy may also elicit local and systemic antitumor immunity, which may be augmented by immunotherapeutic agents including Toll-like receptor (TLR) 7/8 agonists. Here, we investigated the ability of 3M-011 (854A), a TLR7/8 agonist, to boost the antigen-...

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Detalles Bibliográficos
Autores principales: Schölch, Sebastian, Rauber, Conrad, Tietz, Alexandra, Rahbari, Nuh N., Bork, Ulrich, Schmidt, Thomas, Kahlert, Christoph, Haberkorn, Uwe, Tomai, Mark A., Lipson, Kenneth E., Carretero, Rafael, Weitz, Jürgen, Koch, Moritz, Huber, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467106/
https://www.ncbi.nlm.nih.gov/pubmed/25609199