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Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors
In addition to local cytotoxic activity, radiotherapy may also elicit local and systemic antitumor immunity, which may be augmented by immunotherapeutic agents including Toll-like receptor (TLR) 7/8 agonists. Here, we investigated the ability of 3M-011 (854A), a TLR7/8 agonist, to boost the antigen-...
Autores principales: | Schölch, Sebastian, Rauber, Conrad, Tietz, Alexandra, Rahbari, Nuh N., Bork, Ulrich, Schmidt, Thomas, Kahlert, Christoph, Haberkorn, Uwe, Tomai, Mark A., Lipson, Kenneth E., Carretero, Rafael, Weitz, Jürgen, Koch, Moritz, Huber, Peter E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467106/ https://www.ncbi.nlm.nih.gov/pubmed/25609199 |
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