p53 activates G(1) checkpoint following DNA damage by doxorubicin during transient mitotic arrest

Recovery from DNA damage is critical for cell survival. The serious damage is not able to be repaired during checkpoint and finally induces cell death to prevent abnormal cell growth. In this study, we demonstrated that 8N-DNA contents are accumulated via re-replication during prolonged recovery per...

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Detalles Bibliográficos
Autores principales: Hyun, Sun-Yi, Jang, Young-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467116/
https://www.ncbi.nlm.nih.gov/pubmed/25605022

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