Cargando…

Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers

Mutations in 16 targetable oncogenic genes were examined using reverse transcription polymerase chain reaction (RT-PCR) and direct sequencing in 285 Chinese cervical cancers. Their clinicopathological relevance and prognostic significance was assessed. Ninety-two nonsynonymous somatic mutations were...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiang, Libing, Li, Jiajia, Jiang, Wei, Shen, Xuxia, Yang, Wentao, Wu, Xiaohua, Yang, Huijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467127/ https://www.ncbi.nlm.nih.gov/pubmed/25669975

Ejemplares similares

PIK3CA mutation analysis in Chinese patients with surgically resected cervical cancer
por: Xiang, Libing, et al.
Publicado: (2015)

Mutational analysis of KRAS and its clinical implications in cervical cancer patients
por: Jiang, Wei, et al.
Publicado: (2018)

Conization Using an Electrosurgical Knife for Cervical Intraepithelial Neoplasia and Microinvasive Carcinoma
por: Xiang, Libing, et al.
Publicado: (2015)

Distal pancreatectomy with splenectomy for the management of splenic hilum metastasis in cytoreductive surgery of epithelial ovarian cancer
por: Xiang, Libing, et al.
Publicado: (2016)

Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients
por: Wang, Rui, et al.
Publicado: (2015)

A comprehensive study on the oncogenic mutation and molecular pathology in Chinese lung adenocarcinoma patients
por: Zhang, Xilin, et al.
Publicado: (2020)

Recurrence Patterns and Survival Outcomes in Chinese Patients with Surgically Treated Recurrent Ovarian Clear Cell Carcinoma: A Single Institutional Analysis of 45 Cases
por: Ye, Shuang, et al.
Publicado: (2020)

The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer
por: Jiang, Wei, et al.
Publicado: (2018)

(18)F-FDG PET/CT-based metabolic metrics in recurrent tumors of ovarian clear cell carcinoma and their prognostic implications
por: Ye, Shuang, et al.
Publicado: (2019)

The kinetic profile and clinical implication of SCC-Ag in squamous cervical cancer patients undergoing radical hysterectomy using the Simoa assay: a prospective observational study
por: Ye, Shuang, et al.
Publicado: (2020)

Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients
por: Chen, Qiong, et al.
Publicado: (2018)

Clinical significance of peripheral blood and tumor tissue lymphocyte subsets in cervical cancer patients
por: Wu, Yutuan, et al.
Publicado: (2020)

Establishment and molecular characterization of a human ovarian clear cell carcinoma cell line (FDOV1)
por: Jiang, Wei, et al.
Publicado: (2018)

The role of [Formula: see text] F-FDG PET/CT-based quantitative metabolic parameters in patients with ovarian clear cell carcinoma
por: Ye, Shuang, et al.
Publicado: (2020)

The surgical outcomes and perioperative complications of bowel resection as part of debulking surgery of advanced ovarian cancer patients
por: Ye, Shuang, et al.
Publicado: (2022)

Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer Patients
por: Yang, Jie, et al.
Publicado: (2021)

PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer
por: Liu, Lianqin, et al.
Publicado: (2023)

Multiple oncogenic mutations related to targeted therapy in nasopharyngeal carcinoma
por: Zhang, Jian-Wei, et al.
Publicado: (2015)

Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype
por: Holloway, Kimberly R., et al.
Publicado: (2016)

Comprehensive analysis of lncRNAs microarray profile and mRNA–lncRNA co-expression in oncogenic HPV-positive cervical cancer cell lines
por: Yang, LingYun, et al.
Publicado: (2016)

Diaphragmatic Surgery and Related Complications In Primary Cytoreduction for Advanced Ovarian, Tubal, and Peritoneal Carcinoma
por: Ye, Shuang, et al.
Publicado: (2017)

Oncogenic GNAQ and GNA11 Mutations in Uveal Melanoma in Chinese
por: Xu, Xiaolin, et al.
Publicado: (2014)

Association between secondhand smoke exposure and abnormal cervical cytology: A one-to-one matched case-control study
por: An, Libin, et al.
Publicado: (2018)

Comprehensive profiling and quantitation of oncogenic mutations in non small-cell lung carcinoma using single molecule amplification and re-sequencing technology
por: Zhang, Shirong, et al.
Publicado: (2016)

Double agents: genes with both oncogenic and tumor-suppressor functions
por: Shen, Libing, et al.
Publicado: (2018)

A Comprehensive Analysis of Metabolomics and Transcriptomics in Cervical Cancer
por: Yang, Kai, et al.
Publicado: (2017)

Homologous recombination repair gene mutations show no survival benefits in Chinese high-grade serous ovarian cancer patients
por: Feng, Zheng, et al.
Publicado: (2021)

Oncogenic mutations of thyroid hormone receptor β
por: Park, Jeong Won, et al.
Publicado: (2015)

β-Catenin: oncogenic role and therapeutic target in cervical cancer
por: Wang, Bingqi, et al.
Publicado: (2020)

Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology
por: Ibarrola-Villava, Maider, et al.
Publicado: (2016)

Targeting Bcl-2 stability to sensitize cells harboring oncogenic ras
por: Peng, Bo, et al.
Publicado: (2015)

Oncogenic secretory clusterin in hepatocellular carcinoma: Expression at early staging and emerging molecular target
por: Zheng, Wenjie, et al.
Publicado: (2016)

Comprehensive genomic variation profiling of cervical intraepithelial neoplasia and cervical cancer identifies potential targets for cervical cancer early warning
por: Huang, Jian, et al.
Publicado: (2019)

ALK-Rearranged Lung Cancer in Chinese: A Comprehensive Assessment of Clinicopathology, IHC, FISH and RT-PCR
por: Li, Yuan, et al.
Publicado: (2013)

Identification and analysis of mutational hotspots in oncogenes and tumour suppressors
por: Baeissa, Hanadi, et al.
Publicado: (2017)

Mitochondrial Protein UQCRC1 is Oncogenic and a Potential Therapeutic Target for Pancreatic Cancer
por: Wang, Qing, et al.
Publicado: (2020)

Targeting oncogenic mutations in colorectal cancer using cryptotanshinone
por: Vundavilli, Haswanth, et al.
Publicado: (2021)

Human Papillomavirus Type 16 E1 Mutations Associated with Cervical Cancer in a Han Chinese Population
por: Yao, Yueting, et al.
Publicado: (2019)

Analysis of mutational and clinicopathologic characteristics of lung adenocarcinoma with clear cell component
por: Gu, Chang, et al.
Publicado: (2016)

Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma
por: Cui, Xiao-Bin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ou11afdvt7o6l2pk9rtpake9dr